MTHFR : How It Impacts Your Cancer Risk.

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The most common gene that most people have heard about is MTHFR. It is the gene that converts folate (which comes from food) into a form that can methylate toxins.

It was estimated that 47% of the population are poor methylators from genetic standpoint.

There are many other genes that influence methylation. And even more genes that influence your body’s ability to process toxins out to keep your biochemistry optimized.

What this means is that daily, you are accumulating toxic/ foreign molecules in your body’s biochemistry.

You require an efficient liver enzyme system that can process all this quickly and efficiently.

The more toxins you are exposed to, the more the system gets backed up. It’s like a traffic jam.

When this happens, cellular machinery slows down.

The functions of each cell and body system can get affected. Some symptoms include:

  • Low energy
  • Brain fog
  • Immune system dysfunction including autoimmune disease, cancer, allergies, eczema, hayfever, environmental allergies, runny-itchy eyes/ nasal congestion.
  • Poor focus and concentration, and ADHD symptoms
  • Stubborn fat and trouble losing weight
  • Hormone imbalance
  • Low sex drive 
  • Low stamina and endurance

You can eat as many green leafy vegetables as you possibly can but you will not be able to able to activate folate if your MTHFR gene is not coding.
Methylation is vital in metabolizing estrogen and testosterone into safe byproducts and also for brain chemistry.
*** Add estrogen metabolism pathway here.
When it comes to breast cancer, and prostate cancer risk reduction/ prevention – there are 3 key things you need to have happen:
1. Eliminate toxic molecules.
Low, ideally no toxic molecule buildup in your body.
Even if all your detoxigenomic genes work perfectly, the world has gone crazy and there are over 104000 new man-made molecules around you. When there’s a traffic jam, there’s nothing enzymes can do to speed up.
2. A healthy immune system.
Cancer is a result of low functioning immune system.
Because you have 2 arms of your immune system, even if you don’t get sick, or rarely get a
cough and cold; you can still get cancer or autoimmune disease.
Toxins impair how well your immune system can work.
Cortisol, your stress hormone, also affects how your immune system works.
The 3rd thing you need for optimal immune system function is to have the nutrients (both micronutrients – which refers to vitamins and minerals – and macronutrients – in this case, protein is the most important.
3. Optimal Methylation
Methylation neutralizes the pro-cancer metabolites of estrogen and testosterone. Since your body makes these hormones until you reach menopause or andropause, you need optimal methylation.
Methylation is important for brain chemical formation like Dopamine.
Because there is no specific disease or symptom profile that fits this genetic issue, and because there are so many combinations of genes that optimize methylation, it is not recognized as an issue in the traditional medical model. Furthermore, epigenetics (the way genes express themselves based on the internal environment of your body) influences how well, or not, your genes control this process.
People experience many health issues that resolve when they attend to methylation, and detoxification.
In addition to the list above, many patients suffer with infertility or irregular menstrual cycles.
What can you do?
1. Minimize your exposure to toxic molecules.
Think about it in categories to help you identify where you can make impact and changes.
Focus on natural ingredients and ingredients you can easily pronounce and identify.

– Home
Take it room by room. These are not complete lists in the examples.

Laundry (think of laundry detergent, dryer sheets that contain VOCs, stain removers, and bleach)
Bathroom (eg. Toilet bowl cleaner, tub, and tile, air fresheners)
Kitchen (antibacterial cleaners, dish detergent, countertop shiners, stovetop cleaners)
– Body care
Personal care products and products used to enhance appearance are highly laden with molecules that are foreign to your body. Even worse, they disrupt hormones, and like to sit in fatty tissue.
Consider hair spray, dyes, nail polish, and all the different products you use on your face and body.
– Food and water
Fresh produce is sprayed with herbicides, pesticides, glyphosate, and mother chemicals. 
Packaged and processed food is filled with additives, preservatives, and dyes that are derived from coal tar or man made that have been shown to disturb how your body can work.
Tap water contains high amounts of chlorine and many communities add fluoride to the water supply.
Drug residues and metabolites are found in water supplies.
– Environment 
Air quality and contents. 

You cannot control the air outside your home.

Air fresheners, perfumes, mold spores, off-gassing from renovations, new furniture, and new items around the house are breathed in even while you sleep.

– Habits and Hobbies
Consider the chemicals you are exposed to if you love gardening, painting, fixing things, renovations, for example.
2. Support your detoxification pathways:
You can only do this with nutritional supplements.
Super B and the Metabolic Optimizer contain methylfolate. This is the molecule needed to methylate.
Glutathione, and other nutrients like NAC, alphalipoic acid, glycine, and magnesium help support the liver enzyme pathways involved in removing toxins from your biochemistry.
Taking methylfolate by itself is not recommended since all the B vitamins work together to facilitate biochemical pathways.
3. Ensure regular bowel movements. Many toxic molecules, once ready to be removed, require bowel movements to leave your body.
When you are constipated, they transport/ recirculate in your body.
4. Sweat!
Perspiration is another route to eliminate toxins.
5. Take multivitamins: and essential nutrients to improve cellular health. Food no longer has everything you need to be perfectly healthy.
6. Eat fiber: When choosing vegetables, choose those that contain the highest amount of fiber.
Add Psyllium and Chia seeds to your salads and smoothies.
7. Drink lots of water.
The ideal BASE amount of water you need to consume is half your body weight (in pounds) which gives you the number of ounces you need to drink.
Exercise and saunas increase your fluid requirements.
Urine is another route to excrete toxins. Ensure you drink enough water to keep your urine light in color.
8. Add bitterness to your diet.
Arugula, dandelion greens, radicchio, and Swedish bitters stimulate your gall bladder.
Your gall bladder and bile are very important in the detoxification process.
9. Avoid Omega 6, Omega 9, transfats, and seed oils.
Seed oils especially are inflammatory. 
Certain fats and omegas damage the cell membrane and replace the healthy phospholipids in the cell membrane. A dysfunctional cell
The membrane cannot allow toxic molecules out of the cell.
10. Avoid liver toxins.
Alcohol is the most common liver toxin in the modern world today. It is a legal drug and socially acceptable. It slows down the liver enzyme pathways.
Drugs like acetaminophen also damage the liver. 
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